industry report

Where protocol meets practice: What the experience of site teams can teach us about clinical studies

Based on day-to-day experiences of 100 patient-facing site staff across 8 countries, this new report captures the perspectives, expertise, and practical challenges site staff navigate as key members of the trial team.

Rather than prescribing one-size-fits-all solutions, it surfaces what site staff say they need most, and where current approaches fall short.

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Research shows clinical trial success hinges on the participant–study team relationship. Building on insights from our 2025 report, The participation equation, this new research turns the focus to study teams, exploring the realities of their role and the interactions that shape trial experiences and outcomes.
86
%
of site staff interviewed said they would like more training on how best to engage with participants
33
%
cited lack of patient awareness around clinical trials as the largest barrier in patient onboarding
28
%
of site staff named interpreting protocols as the most prevalent daily challenge

We are Cuttsy+Cuttsy, the original patient communications agency specialising in clinical trial engagement.

As a trusted clinical trial and healthcare communications partner to the pharmaceutical industry since 2011, we’ve supported over 110,000 trial participants, across all major therapy areas, in more than 40 countries.

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